Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists
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چکیده
منابع مشابه
Two Janus Cannabinoids That Are Both CB2 Agonists and CB1 Antagonists.
The cannabinoid signaling system includes two G protein-coupled receptors, CB1 and CB2 These receptors are widely distributed throughout the body and have each been implicated in many physiologically important processes. Although the cannabinoid signaling system has therapeutic potential, the development of receptor-selective ligands remains a persistent hurdle. Because CB1 and CB2 are involved...
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ژورنال
عنوان ژورنال: Journal of Pharmacology and Experimental Therapeutics
سال: 2016
ISSN: 0022-3565,1521-0103
DOI: 10.1124/jpet.116.236539